MBS 430 Systems Immunology • 5 Cr.
This course is an introduction to molecular immunology. Topics include an overview of the immune system, antibody and T-cell receptor structure and function, genes of the immunoglobulin family, cells and molecules that mediate the immune response, and medical applications of modern immunology. Prerequisites: MBS 340 and CHEM 406 and with a C or higher.
After completing this class, students should be able to:
- Identify the components of the immune system.
- Illustrate in detail the structures of antibodies and T-cell receptors and the interaction between antigens and antibodies.
- Examine the role of major histocompatibility complex (MHC) molecules in immune responses.
- Explain T and B-cell activation by antigens and the generation of antibody and T-cell receptor diversity.
- Classify cell types, molecules and pathways by their innate and antibody-mediated effector functions.
- Explain the molecular and cellular interactions in inflammation.
- Discuss the innate and adaptive defense mechanisms against different microbes.
- Discuss the role of the immune response in health and disease.
- Examine current immunotherapeutic approaches.